Tomorrow I have a series of tests including a PET Scan, as part of the continued pre-surgical testing for epilepsy surgery. Joy. - / -
One of the most effective treatments for partial epilepsy in patients refractory to medical interven- tions is surgical removal of the involved area, both in the pediatric and adult populations. Using high- resolution PET imaging, accurate localization of seizure foci can be achieved to help select appropriate candidates for surgical intervention [3â5,8,22]. Stud- ies have also found that after surgical excision of the seizure foci, there is usually significant improvement in the function of the rest of the brain
Seizure disorders often begin in childhood and are treated with a variety of pharmacologic or surgical interventions for those refractory to medical therapy. Functional imaging, with both PET and single-photon emission CT (SPECT), has been highly useful in the diagnosis, management, and follow-up of patients with seizure disorders (Fig. 1). The ability of functional imaging to provide important information about seizures derives from the fact that epileptic conditions result in significant physiologic alterations in the brain. These physiologic changes occur both during sei- zures and in the interictal state. Because generalized seizures affect a large part of the brain, it is typically more difficult to isolate the originating focus from other areas that are secondarily affected on functional imaging studies. For partial seizures and other types of seizures that originate from a specific focus, however, functional imaging can be useful for local- izing the primary site. Functional imaging also helps in the understanding of the pathophysiology of seizure disorders.